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KMID : 0375219940090010123
Journal of Il Sin Christian Hospital
1994 Volume.9 No. 1 p.123 ~ p.132
Clinical Evaluation of Severe Ovarian Hyperstimulation Syndrome
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Abstract
Ovarian hyperstimulation syndrome (OHSS) is appeared as a complication of ovulation induction agents used for ovulatory dysfunction.
From January, 1989 to February, 1995, 14 cases913 patients) were hospitalized for the management of OHSS and treated conservatively with infusion of crystalloids and albumins. Therapeutic paracentesis was performed in 10 cases. Clinical symptoms,
signs,
hospital courses, treatment measures and associated pregnancies were evaluated in the records of 14 cases (13 patients) retrospctively.
@ES Results were as follows:
@EN 1. The mean age of 14 cases was 27.8 years. The regimens for controlled ovarian hyperstimulation were FSH/hMG/hCg in 10 cases and FSH/hCG in one case. In the rest of 3 cases, the regiments wee unknown due to transfer to hospital.
2. The most common symptom was abdominal pain. Abdominal distention, epigastric discomfort, dyspnea, nausea, vomiting and diarrhea were presented in order of frequency. Ovarian enlargement and ascites were present in all cases.
3. The duration from hCG injection to hospital admission was 12.7 days, and the hospital stay renged from 2 days to 21 days with an average of 9.4 days.
4. In 10 cases (71.4%), ovarian hyperstimulation was associated with conception including one twin gestations. Spontaneous abortion occurred in 4 cases(40%), ectopic pregnancy in one case (10%), and premature delivery in one case(10%). Casarian
section
was done at term in 2 cases (20%), and normal vaginal delivery at term in one case(10%).
5. Paracentesis under ultrasonographic guidance was performed in 10 cases through 18 times with an average amount of 2157ml per one time and in transvaginal route except two transabdominal routes. There was no serious complcation after
paracentesis.
In conclusion, OHSS was usually associated with pregnancy and recovered with conservative treatement including ultrasonography-guided paracentesis without any serious coplication.
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